A Bad Memory Erasing Pill

The February issue of Wired magazine contained an article about an interesting medical breakthrough related to memory. Scientists working on the development of a pill that can erase bad memories have achieved success in laboratory rats.

memory erasing pill

Bad memories, a thing of the past?

It is a long and detailed article, but I will try to summarize it in a few sentences. Memories are stored in different parts of the brian, emotions in one part, visuals in another etc. In order to remember something a sort of chain must be formed that link the separate parts of the memory, a chain formed by protein. If you can block the protein you can block access to the memory.

Scientists have been experimenting for decades to try and find a compound that can do this, and recently seem to have found one that works on rats. The experiment is relatively simple, the rats are exposed to series that they learn to recognize, an example might be a series of musical notes followed by a painful electric shock. As soon as the rats hear the first note in the series they get scared and agitated. Administer the compound and the association is lost, you can play the series and the rats no longer remember the consequences until BANG, the shock arrives.

Cruel but bearing important consequences, if the links in the chain can be broken then the memory is not cancelled but the individual no longer has access to it.

As I said above different parts of the memory are stored in different places, so the hope is that different compounds will be able to delete different aspects of painful memories. One might close access to the memory of the scent of an ex girlfriend who left you for your best mate, or the pain experienced in an accident, or the vision of your dog jumping out of your third floor bedroom window while chasing a ball that you accidentally threw too hard for him to catch, or other such traumas.

Talk is of selected memory loss by pill, but of course this is far in the future if ever at all, but the very prospect raises some interesting ethical dilemmas. We are who we are by experience. I don’t play with knives; I have a scar with 7 stitches in my hand to remind me why, but even without it the memory of a Christmas Eve trip to Wythenshawe Hospital lingers on.

And having seen various governments conduct more than questionable research on their own populations (and others) and I am not just talking about despot regimes but the very birth states of democracy themselves as this apology given by President Obama demonstrates, I sincerely question the ethics behind such a development.

So the question is this, are we seeing a great medical and technological breakthrough, a leap in human advancement, or the creation of another dangerous tool once it gets into the wrong hands?

Nanobots – The future in Nanotechnology

This is Technology Bloggers 150th article 🙂
Well done and thank you to all our brilliant writers (Hayley included), as well as readers and commenters who have helped us get here!

A fraction of the ever-expanding field of nano-technology, nano-robots, a.k.a. nanobots, hold some of the most promising possibilities in the fields of technology, engineering and medicine. They also pose some of the most complex hurdles, such as automation, replication, control and finding viable energy sources to enable movement.

The Nano-Scale

Nanotechnology involves the study and micromanipulation of anatomic particles up to 1 nanometer, with scientists working to develop nanobots in fields less than 100 nanometers in size. Transmission electron (TEM), scanning electron (SEM), scanning tunneling (STM) and Atomic Force (ATM) microscopes are large, powerful machines that make all aspects of nanotechnology, including nano-robotics, possible.

Nano-microscopes allow researchers to isolate and observe single molecules, including chemical reactions that occur upon moving, eliminating and rearranging molecular structures. This base knowledge is essential to understanding, creating and ultimately finding solutions so that nanobot technology will reach its full potential.

Bottoms Up

Up until recent years, the development of nanotechnologies maintained “top-down” construction. The advent of “bottom up” creations on the nano-scale provide scientists the ability to create smaller objects; in addition, components can be “grown” to allow greater adaptation to specific environments or inclusion of specific properties.

Scientists are literally able to “grow” carbon nanotubes and “string” together nanowires, creating desired properties such as hastening conduction or reducing heat output – properties that make for tiny, efficient particles. In theory, by building a nanobot from the bottom up, scientists begin to find solutions that allow for greater control mechanisms and possibly self-replication of the nanobot.

A carbon nanotube

Carbon nanotubes – building nanotechnology from the bottom up.

The greatest benefit of working bottom-up is that, rather than altering materials to work in a desired fashion, scientists build nanostructures and nanobots with proper compounds from the outset.

The Present

Although practical applications in medicine and technology have yet to be fully realized, nanobots are no longer figments of science-fiction imagination.

Lack of autonomy, largely associated with insufficient or unrealistic sources of energy, leaves a large barrier to the potential uses of nanobots. Batteries and solar sources are impractical due to size and, although a scientist can guide the nanobot with the use of magnets, they are not ideal. For example, a physician using a nanobot to treat a patient would need to maneuver the nanobot from outside the skin while also observing inner structures of the body.

Within the past year, scientists announced the creation of a nano “electric motor.” Utilizing principles of adsorption, a molecule attaches itself to the outside of a piece of copper; an STM probe focuses electrons onto the molecule, providing a source of energy and means to control direction. The large, cumbersome STM still makes this impractical in many ways; however, scientists are able to study this single motor and hypothesize ways to alter this and thus to apply it to nanobots.

In addition, micromanipulation made possible by electron microscopes allows for “DNA-walkers.” Essentially reprogramming a portion of a DNA strand, “molecular robots” or “spiders” walk autonomously; ultimately, scientists hope to further develop this technology, creating nanobots that fix genetic diseases.

The Future

Many scientists believe self-replication, most likely by programming the nanobot to micromanipulate surrounding atoms to create duplicates of its self, is essential to the realization of the many medical and technological applications.

In addition, a truly autonomous nanobot would be able to recognize, react and/or adjust to varying environmental conditions, including the presence of other nanobots; scientist could also program them for molecular assembly.

Many believe nanobots will allow for precise diagnostic capability and treatment of diseases such as cancer, as well as genetic disorders. Advances in communications, green energy, computer electronics and semi-conductors appear limitless.

Summary

Although still in its infancy, scientists across many fields hold much promise for nanobot technology. An autonomous nanobot, able to adapt its environment and self-replicate, could be the key to early detection and the cure of many diseases; in addition, nanobots will play an important role in sustainable or renewable energy sources, engineering and advancing computer technology. What do you think?

For further information check out the article on nanobots over at MicroscopeMaster. Links in my bio.

The BOINC Home Network

A few months ago, I wrote about LHC@home 2.0, which is a project that you can get involved in that allows you to use your spare computing capacity to help ‘crunch’ scientific data from the Large Hadron Collider project.

Rather shamefully, at the time of writing the article, I hadn’t actually taken part in the project, however after buying a new PC, I thought that it was my duty to donate my spare processing power to help science!


I started off by going to the SETI@home website, where I worked out that in order to take part in the search for extraterrestrial intelligence (SETI) project, I would need to download the ‘BOINC software’ – so I did. When I installed the software I was amazed with the amount of different projects that I was able to partake in.

The BOINC software is effectively a management tool which lets you choose which projects you want to help crunch data for. Then it sets about downloading, analysing and then uploading the data in the background.

The BIONIC LogoThere are so many great projects that people can get involved in, from looking for extraterrestrial life and the Higgs particle, to projects providing power to those who are doing vital research into malaria, cancers and other important global diseases, and even trying to work out how and why gravity works!

From finding new medicines to helping university students, there really is something for everyone to get involved in.

If you are worried that it may slow down your computer, then don’t be, you can set how much of your processor BIONIC can use, as well as the amount of hard disk space it can take up, and also how it uses your internet.

The BOINC software comes with an easy to follow interface, and gives you announces of important events and discoveries relating to @home projects.

The BOINC Manager Interface

The BOINC Manager Interface

Think where we would be in terms of scientific advancements, if everyone were to give just 10% of their PC to some of BOINC’s @home projects.

You can make a difference, and you can help science! Please go to the BOINC website to download the software today, and get stated with some of the brilliant projects they have on offer! I personally believe that the following projects are really worth a look at:

  • Poem@Home – investigating protein structures, how they determine protein function, how they interact with one another, etc.
  • LHC@home 1.0 – the Large Hadron Collider project – with some extra software, you can also take part in LHC@home 2.0
  • climateprediction.net – attempting to improve climate modelling, and predict the possible effects of climate change
  • Einstein@Home – searching through data from the LIGO detectors for evidence of continuous gravitational-wave sources, as well as searching radio telescope data from the Arecibo Observatory for radio pulsars
  • Cosmology@Home – comparing theoretical models of the universe in order to try to improve future technologies
  • malariacontrol.net – helping in the fight against malaria, via creating simulations and models of the history of Malaria
  • SETI@home – analysing data from outer space, to try and find extraterrestrial life

Unfortunately, I now have to give you a warning. Whilst I am sure that the software and projects are all 100% safe to participate in, some organisations would not want you to install them on their computers. You would be perfectly okay to install such projects on your home PC, however I wouldn’t advise that you do it at work or school, as there have been incidences in the past of firms pressing charges against people for increasing their internet usage and filling up there serves by unauthorised software like BOINC.

That aside, I really do urge you to download the BOINC manager today, any start helping science! If this makes the offer any more attractive, most projects have their own screensavers, many of which look pretty cool!

Install it and leave a comment below to let us know how you are getting on 🙂