Online Gamers as Scientists

If you thought that online gamers were just a load of geeks, incapable of socializing with the outside world, and living within the confines of their own in their bedrooms, you might like to have a look this website called Foldit. Foldit is a game, but its aim is to solve puzzles for science, and players have recently made some remarkable inroads into the world of protein modelling. Below is a model of an Amino Acid, and it is this type of thing that gamers manipulate.
An Amino Acid Protein MoleculeThis article that explains the process is in the online journal Nature, Structure and Molecular Biology, and begins with the following statement:

“Following the failure of a wide range of attempts to solve the crystal structure of M-PMV retroviral protease by molecular replacement, we challenged players of the protein folding game Foldit to produce accurate models of the protein. Remarkably, Foldit players were able to generate models of sufficient quality for successful molecular replacement and subsequent structure determination. The refined structure provides new insights for the design of antiretroviral drugs.”

The fold it game has existed for a couple of years now. Players create protein structures, with the most stable and low energy structures scoring the most points.

The gamers in general are not scientists and they manually manipulate the model from a base form that is provided to them at the start of the operation. They have a variety of tools but the most important thing is that they have better spatial reasoning skills than computers. Computer models had tried to solve the problem cited above for 10 years without success, gamers produced an adequate model that was then refined by scientists in just 3 weeks.

We could draw similarities to citizen science, having seen posts on this blog discussing loaning out some of your computer’s spare hard disk space and memory to solve scientific problems, and the now common use of similar set ups in astronomy.

Just this week the Astronomy and Telescope journal is entitled Citizen Science, and addresses the issue of amateurs classifying high definition photos of far off galaxies. They say that it is the future of astronomic discovery. See my post on The Bassetti Foundation website for a lay explanation.

The gaming process is an interesting innovation though, as it uses skills that may not be particularly associated with science, but reveal themselves to be extremely important.

Everything There is to Know About GTA V as of August 2011

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About this time last year, game sites were abuzz with rumours that the next instalment of Rockstar’s immensely successful Grand Theft Auto series was headed toward the west coast of the United States.

The New York-based video game publishing company’s California division, Rockstar San Diego, was discovered to be scouting sites in and around Hollywood and the greater Los Angeles area. Fans were fluttering with curiosity – were they going to return to the streets of Los Santos and Vinewood, featured prominently in the 2004 GTA release “San Andreas?”

Another article on everyone’s minds was and still is what time period the next instalment will be set in; since Rockstar has spanned the series across decades. Will the next character be accessing menu options through an altered version of an HTC 4G Android phone similar to the last game, or will we be sent backward in time once again and forced to rely on payphones?

As far as the rumours from the summer of 2010, not much has come up to confirm the initial suspicions about an American west coast location. Perhaps Rockstar San Diego was doing some last-minute research for their spring 2011 release L.A. Noire. However, in-depth news on the game had already been released by March of 2010 so it’s doubtful they were doing location scouting after-the-fact. Not to mention, sources confirm that the environment of L.A. Noire, set in 1947, was created with aerial maps from the era.

So what’s to know about the next instalment of Grand Theft Auto? We know it’s going to happen soon: Rockstar’s mother-company Take-Two Interactive is expected to sell 18 million copies of the next instalment of GTA. We know it’ll be a cross-platform release like GTA IV. We know it won’t be set in Liberty City, where the historical Grand Theft Auto III was set and where the last one was set as well.

Take-Two Interactive's LogoThe details we want to know remain elusive, but there’s been some interesting tidbits released over the last year. In February of 2011, Rockstar purchased several specific domains which hallmark a previous gag featured in GTA IV wherein the character can visit websites that exists in real life for gamers to visit too. In that same month, a stuntman credited on previous instalments of the series listed “Grand Theft Auto V” on his acting resume, but later changed it, saying the credit was a “typo”.

But the big kahuna came later in March when a Take-Two casting call was leaked which included the name of a deviant character by the name of James Pedeaston heard on the radio in GTA IV, as well as another presumed radio personality character named Samantha who “dreams of being a Hollywood celebrity.” This could be interpreted as confirmation of the rumored Hollywood setting.

The revelation has been that unless Rockstar is playing games so to speak, which they’re no strangers at doing, the next Grand Theft Auto game will definitely be set in the present day. Other than that, details remain extremely limited. Just count on the fact that the game will be controversial, environmentally jaw-dropping, and sure to make its creators an enormous amount of money at a time when game developers are struggling to pay the bills.